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Voluntary running Ten-week-old male C57BL/6J mice on a chow diet were single-housed in cages equipped with running wheels (23 cm in diameter, Techniplast I)

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doi:10.1186/s13024-026-00925-5 53

For the PWA model of persistent hyperandrogenism, none of the multi-agonist was able to substantially ameliorate the state of reproductive dysfunction, as manifested by a lack of effects on sex organ weights or reproductive hormone levels, as well as by the failure to rescue ovulation