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All RE trials were supervised by experienced instructors to ensure appropriate form

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However, as genotyping is not currently routinely available and serum vitamin B 12 measurement is cheap, our results reinforce the causal association of metformin treatment with vitamin B 12 deficiency and guideline recommendations for routine screening for vitamin B 12 deficiency in people treated with metformin

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GeroScience, 45 (1), 29-43