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Indicated especially when neurological signs or severe anemia are present

Determining synergy The Chou-Talalay method was employed to determine synergy (Chou, 2006) using constant-ratio matched titrations (0.125X, 0.25X, 0.5X, 1X, 2X, 3X, 4X, and 8X) of multiples of the Cmax (500 nM for DAC, 132 M for paracetamol) and assessed by cell viability

Similarly, specialized laboratory testing can assess markers of oxidative stress and glutathione status, potentially allowing for more targeted protocols based on actual deficiencies rather than presumed needs