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Dosing by body weight category Under 160 pounds (72kg): Start with 300mcg daily

PT-141 INJECTOR PEN 3ML PT-141 (bremelanotide) is a synthetic peptide analogue of alpha-melanocyte-stimulating hormone that acts at the melanocortin receptors MC3R and MC4R

Pharmacokinetic studies in rats demonstrated an oral bioavailability of 38.4%, with a mean Cmax of 2,252 ng/mL and terminal elimination half-lives of 3.80 1.10 hours (IV) and 6.90 1.20 hours (oral) (Awosemo et al., 2021)

The two mechanisms can be complementary in some plans

They primarily work by mimicking a gut hormone that slows digestion, reduces appetite, and improves insulin secretion