Second is the role of PA in attenuating oxidative stress, which in turn may lead to increased SIRT-1 expression ( SIRT-1 upregulation (Zhang and Tang, 2023)
Author AB has received speakers fees from AbbVie, Galapagos, Celltrion and Pfizer
Studies also indicate that zinc supplementation in type 2 diabetes mellitus patients can reduce fasting blood glucose, HbA1c, and lipid profiles, including TC and LDL-C, while increasing HDL-C, highlighting its potential as a beneficial adjunct therapy for older adults with diabetes [455, 594, 595]
J Biol Chem 278, 1390513911, doi: 10.1074/jbc.M211976200 (2003)
PANC-1, MIA PaCa-2 and HPNE cells were cultured in DMEM (Biological Industries, Beit Haemek, Israel) containing 10% fetal bovine serum (FBS, Biological Industries, Beit Haemek, Israel)