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INTRODUCTION Schizophrenia (SZ) is a common and highly disabling mental disorder without a clearly identified pathophysiology

It offers a simple way to manage B12 needs and often works well to address deficiencies caused by diet

The real human data belong to different molecules/uses

This repeated freezethaw approach may have broad application for other proteins expressed in the form of inclusion bodies for which low yields are observed following a single round of freezethaw