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Chronic stress models in rodents are used to understand how the brain translates stress into depressive-like symptoms and physical changes in brain structure [51, 57]

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Longevity and Anti-Aging Protocols The mitochondrial decline associated with aging is one of the most well-documented contributors to age-related disease

While preclinical studies consistently demonstrate benefits in models of Alzheimer's disease, Parkinson's disease, multiple sclerosis, and amyotrophic lateral sclerosis (ALS), clinical trial outcomes have been variable, largely owing to heterogeneity in study populations and trial design