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This overlap is one reason the mechanistic story feels compelling

This dual mechanism enhances insulin secretion in a glucose-dependent manner, suppresses glucagon secretion, and slows gastric emptying

In cartilage, chronic inflammation drives osteoarthritis progression destroying matrix faster than chondrocytes can rebuild

On the contrary, alterations in the C-terminal seemed less critical for activity and for instance a deletion of the C-terminal phenylalanine residue of 1 had only a minor impact and the binding affinity was essentially maintained (Sardinia et al., 1993

Many vitamin and mineral deficiencies can cause tiredness and fatigue