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Moreover, it is not known whether the association of GLP1-ra and diabetic retinopathy may be mitigated over time, as short-term tightening of diabetic control can precipitate worsening of diabetic retinopathy, but over the longer-term improved glycaemic control is beneficial in holistic diabetes outcomes

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By targeting the core region, it identifies subtypes 1a, 1b and genotype 6

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Substantial Weight Loss Over 68 Weeks Participants who received the highest dose (12 mg) experienced an average 28.7 % reduction in body weight, equivalent to roughly 71.2 lbs from their starting weights over 68 weeks, far greater than the placebo group, which saw about a 2.1 % reduction