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Abstract To exclude an excess risk of cardiovascular (CV) events, CV outcomes trials (CVOTs) have assessed the effects of new glucose-lowering therapies, including glucagon-like peptide-1 receptor agonists (GLP-1RAs), in patients with type 2 diabetes and established CV disease or CV risk factors

Pancreatic cancer has received particular attention due to the pancreatic expression of GLP-1 receptors and early concerns about pancreatitis potentially increasing cancer risk

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