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Concluding Remarks and Perspectives We reviewed here many in vivo and in vitro experimental studies, implying disturbances of the glutamatergic system caused by metabolites accumulating in various IEMs, which are clinically characterized by convulsions associated with neurodegeneration

Risks include: Contamination with bacteria or fungi Endotoxin (bacterial cell wall fragments) that remain even after sterilization Severe inflammatory reactions or sepsis D

Pfluke JM, Parker M, Bowers SP, Asbun HJ, Daniel Smith C

animal studies examining fermented foods outside the context of maternal nutrition or offspring health

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