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Deferasirox targeting ferroptosis synergistically ameliorates myocardial ischemia reperfusion injury in conjunction with cyclosporine A

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& Skrypnik, D

Indeed, over 110 different compounds, including metals, their oxides, metal salts, drugs, kinase inhibitors, endogenous toxins, inhibitors of signaling pathways, alkaloids and other plant-derived biologically active substances, have been shown to induce eryptosis in vitro at lower concentrations than hemolysis or to a higher extent at the same concentrations [450]