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TB-500 (TB-4) component Two Phase 2 dermal ulcer trials referenced in the Goldstein review (PMID 22074294) reported acceleration of healing without serious adverse events at the studied subcutaneous doses

Rabanel JM, Piec PA, Landri S, Patten SA, Ramassamy C (2020) Transport of PEGylated-PLA nanoparticles across a blood brain barrier model, entry into neuronal cells and in vivo brain bioavailability

The main risk with switching from a compounded to name-brand GLP-1 is from transitioning straight to a high dose (even if on a higher dose of a compounded version), given the risk for potential increased side effects and intolerance, says Stanley