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As expected, the chemically reactive metabolites were much more cytotoxic than their respective precursors and displayed comparable and steep dose-dependent decreases in cell viability ( Figure 2 )

Abell SK, Boyle JA, de Courten B et al (2016) Contemporary type 1 diabetes pregnancy outcomes: impact of obesity and glycaemic control

Despite these insights, certain histopathologic observations within Spitz tumors continue to cloud diagnosis