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[DOI] [PubMed] [Google Scholar] 80.Tanimura H., Minamoto A., Narai A., Hirayama T., Suzuki M., Mishima H.K

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Experimental supplementation studies in women with PCOS reveal that nocturnal melatonin (25 mg) improves fasting glucose, HOMA-IR, and adiponectin levels while reducing androgen concentrations and oxidative biomarkers (199)

The normalization of intestinal permeability, while not formally included among STRIDE-II targets, represents a desirable future endpoint that may further refine the assessment of barrier restoration