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Sim M, Hong S, Jung S, Kim JS, Goo YT, Chun WY, Shin DM

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Subsequent bioinformatics analysis revealed that, in addition to ACC1 and USP22, other classic lipid synthesis genes, including ACLY, FASN, and SCD, exhibited a PPAR-dependent downregulation trend

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A comprehensive exploration of the significance of Gut microbiome and liver detoxification and recognizing the role of the Gut-Liver Axis in these pathologies, not only deepens our understanding of disease mechanisms but also opens avenues for therapeutic interventions aimed at restoring the balance within this complex interorgan communication system