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336 As in vitro models for drug safety evaluation, small and large intestine organoids have been used in toxicology studies to predict drug-induced gastrointestinal toxicity, such as assessing transcriptomic responses associated with viability and apoptosis following exposure to doxorubicin and gefitinib as a physiological endpoint

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In a number of disease states, diffuse fibrosis can be assessed by quantitative CMR relaxometry, incorporating T 1 mapping with high reproducibility, however it was not possible in the present study to include T 1 mapping sequences

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