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Shifting focus from the brands original fiber powders to a capsule formula, ColonBroom targets natural approach to induce GLP-1 release

The likelihood of adverse reactions tends to rise with higher doses

It is recognized that the hydrochloride salt form suppresses NF-B activation, hinders MMPs (MMP-2 and MMP-9) synthesis, and reverses the transition from epithelial to mesenchymal traits in cancerous cells

For Caspase-3 staining, the tissues were blocked with 10% normal horse serum for 30 min then incubated with Caspase-3 antibody (1:300, BD Biosciences, Macquarie Park, NSW, Australia) overnight, followed by secondary antibodies (Goat anti-rabbit HRP, 1:200, Vector Laboratories, Burlingame, CA, USA) for 45 min

Other concerns include hypoglycemia, particularly when GLP-1 RA are used in combination with insulin or sulfonylureas, as well as potential CV effects [73]