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LOX is a non-heme iron-dependent dioxygenase that can directly oxidize PUFA and PUFA-PLs in membranes, leading to ferroptosis [36]

The reason for this discrepancy is not known but could be related to differences in patient cohorts

Instead, they work through several pathways at once, including: Slowing how quickly the stomach empties (which keeps you fuller longer) Reducing appetite signals in the brain Supporting insulin release Blunting glucagon (a hormone that raises blood sugar) Tirzepatide goes a step further by acting on a second hormone pathway (GIP) in addition to GLP-1, which may further support metabolic regulation

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* Depending on the results of the consultation, the physician may determine that the medication cannot be prescribed