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Doskey, C

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however, in some cases this may increase their cytotoxic activity

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To examine whether Ick deficiency affects the distribution of IFT components in photoreceptor cilia, we immunostained retinal sections using anti-IFT88 (an IFT-B component), anti-IFT140 (an IFT-A component), and anti-acetylated -tubulin (Actub, a ciliary axoneme marker) antibodies, and observed no substantial differences between the control and Ick CKO retinas (Fig S1B)