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10.1016/J.TIBS.2015.12.001 45 LinH

Yeh H, Lin C, Li YR, Yen CL, Lee CC, Chen JS, Chen KH, Tian YC, Liu PH, Hsiao CC

Published in vitro work has characterized 5-Amino-1MQ as a competitive NNMT inhibitor with low micromolar potency against the recombinant enzyme, and as a cell-permeable agent that suppresses NNMT activity in cultured 3T3-L1 adipocytes at micromolar concentrations [1]