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While hormone replacement therapy and bioidentical hormones can be helpful for some patients, many women continue to experience low sexual desire despite optimized hormone therapy

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By using lysine derivatives with different side-chain protecting groups (such as Fmoc-Lys(Alloc)-OH or Fmoc-Lys(Dde)-OH), chemists can achieve regioselective side-chain modifications to construct head-to-tail cyclic peptides or side-chain-to-side-chain cyclic peptides