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Retatrutide Research Findings Phase II clinical trial data published in the New England Journal of Medicine (Jastreboff et al., June 2023) reported the following findings in adult participants with obesity over 48 weeks: Up to 24.2% mean body weight reduction at the highest dose (12mg weekly) Significant reductions in visceral adipose tissue Improved fasting glucose and insulin sensitivity markers Reductions in waist circumference averaging 1822cm Greater efficacy than both Semaglutide 2.4mg and Tirzepatide 15mg in indirect comparisons These findings represent some of the most significant weight reduction outcomes ever observed in a clinical trial for a non-surgical intervention, and have driven substantial research interest in the UK and globally

The cell biology of Parkinson's disease