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Malva parviflora Extract (5FAD) reduced microglial pro-inflammatory MI phenotype, promoted phagocytosis via CD36 upregulation, and reduced amyloid plaques

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At higher doses (2.0mg), symptoms may persist for 4-6 weeks

Our combination therapy of (-)-Vestitol and Salviolone, identified via network medicine, targets multiple AD-related pathways, including Neuroactive ligand-receptor interaction and Calcium signaling pathway, potentially offering a more comprehensive, disease-modifying approach