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When such a magnitude of weight reduction is achieved by caloric restriction alone, increases in appetite caused by weight loss-induced modifications in neuroendocrine hormones that regulate hunger (increased ghrelin), satiety (decreased peptide YY, amylin), and fullness (decreased cholecystokinin) would be expected [66]

The company is now testing the molecule in Phase 3 studies

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Studies conducted in laboratory settings seem to indicate that this peptide might impact lipid and glucose metabolism by modulating enzymatic pathways responsible for substrate oxidation and nutrient partitioning

This represents an average additional fat loss of about 1.8 kg (4 pounds) over 12 weeks attributable to the peptide