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One is that GSSG and GS-X produced in cardiomyocytes are pumped out by multidrug resistance protein 1 (MRP1), preventing GSSG or GS-X accumulation in cardiomyocytes [33, 34], and subsequently enter the -glutamyl cycle

Pain over the patellar tendon is the first symptom of patellar tendinitis

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Practical takeaway: FOXO4-DRI's senolytic mechanism is well-established in cell culture and animal models