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doi: 10.1007/s11894-002-0071-6

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In all, mTORC1 signals serve as a central hub of amino acid sensing and a variety of metabolic regulatory pathways, including proteins, nucleotides, and lipids synthesis, as well as other anabolic or catabolic processes (Ben-Sahra and Manning, Amino Acid Metabolism and Epigenetics Epigenetic modification can regulate gene expression by activating or inhibiting gene transcription without changing the DNA sequence, ultimately affecting embryonic development, stem cell differentiation, senescence, and tumorigenesis (Brien et al., 2019)

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