Instead, they actively downregulate the core behavioral features of BED, significantly reducing active binge eating episodes, loss-of-control eating, and emotional eating patterns
When appropriate and with patient consent, I find it valuable to understand the broader treatment context, including how long a patient has been on therapy, whether dosing has changed recently, and what the anticipated long-term plan looks like, since all of these factors shape what aesthetic approach makes the most sense at a given point in time
Using sulforaphane as the model isothiocyanate, it has indeed been established that its metabolites sulforaphane-glutathione, sulforaphane-cysteine-glycine, sulforaphane-cysteine, and sulforaphane N-acetylcysteine collectively known as dithiocarbamates ( Figure 2 ), are ultimately excreted in the urine (4)
This dual action, building new while clearing old, creates the regenerative effect
Although histological reversal of advanced fibrosis remains challenging, GLP-1RAs seem to prevent the progression of fibrosis and may promote the regression of early-stage fibrosis
