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The quick answer for busy clinicians If a colleague asks semaglutide or phentermine? in a hallway, the honest one-sentence version is this: reach for semaglutide when you are treating obesity as a chronic disease that needs durable, year-over-year management, and reach for phentermine when you want an inexpensive, fast short-term jump-start for a motivated patient who does not need or cannot afford long-term pharmacotherapy

Following these steps can make the process smoother and help prevent bruising

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Those with a history of kidney failure or chronic kidney disease should have their kidney function tested regularly

4 Gastrointestinal side effects are common but can be managed