tirzepatide moa Mechanism of Weight Loss & Blood Sugar Control TIRZEPATIDE Mechanism of action of

The right option depends on the individual rather than which medication is receiving the most attention online

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For type 2 diabetes , NICE guideline NG28 recommends considering GLP-1 agonists as an option when: Triple therapy with metformin and two other oral drugs is ineffective, not tolerated, or contraindicated The person has a BMI 35 kg/m (or 32.5 kg/m in people of South Asian or related ethnicity) and specific psychological or medical problems associated with obesity Insulin therapy would have significant occupational implications or weight loss would benefit other obesity-related comorbidities Treatment should be continued only if there is a beneficial metabolic response (HbA1c reduction of at least 11 mmol/mol [1.0%] and weight loss of at least 3% of initial body weight at 6 months)

Benefits: Lowering blood sugar levels helps prevent serious complications of diabetes such as kidney damage, blindness, heart attack, and stroke

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