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76 T eff cells require higher levels of glutamine than nave T cells due to their rapid proliferation and demand for sufficient raw materials for macromolecule synthesis and cytokine secretion

Cell viability and proliferation analysis Cell viability was assessed using trypan blue exclusion assay

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Combination Care May Help Some patients benefit from both approaches: surgery for durable weight loss and medication when additional appetite control is needed

- Improved glycaemic control and cardiometabolic markers (e.g., inflammatory lipids and blood pressure reported in readouts)