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iv) Gastrointestinal Irritation: When the stomach lining gets irritated, it can cause nausea, vomiting, or an upset stomach

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A 2021 peer-reviewed review of NNMT in obesity and type 2 diabetes states explicitly that 'clinical trials targeting NNMT have not been reported' meaning every quantitative efficacy figure available for this compound comes from mice, and there is currently zero published human efficacy data