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To determine the mechanisms and signaling pathways affected by ibuprofen (100 mg/kg/day for seven days), we performed proteomic profiling of male mice liver with quantitative liquid chromatography tandem mass spectrometry (LC-MS/MS) using ten-plex tandem mass tag (TMT) labeling

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HaCaT, human keratinocyte

[ 7 ] Questions arose whether DSIP truly exists as a naturally occurring peptide in humans or whether the observed activity represented related peptide fragments