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Medication interactions also become more complex with age, as older adults typically take multiple medications

J Biol Chem 280, 1418914202, 10.1074/jbc.M413660200 (2005)

Since the underlying mechanisms of muscle atrophy in various diseases are different, it is unlikely the IGF-I would be a universal miracle drug that cures all forms of wasting condition

Carlson AL, Daniel TD, DeSantis A, et al