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Recommended Starting Dose of Retatrutide Phase 2 trial protocols typically initiated retatrutide at 2 mg once weekly via subcutaneous injection, allowing gradual physiological adaptation before dose escalation

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Female C57BL/6 mice were immunised subcutaneously at the tail base on days 0, 21, 28, and 35 with 30 g of VC-13 (or an increased adjuvant-normalised dose according to Table 1)