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Regulatory B cells (Bregs), particularly IL-10producing B10 cells, are decreased or functionally impaired in HT, diminishing control over pro-inflammatory T cell activity (Stafford, EA

Soto, T.J

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Discussion Here, we further interrogated the mechanisms linking mGIPR-Ab/GLP-1 peptideantibody conjugates to weight loss and improved metabolic markers in preclinical and clinical studies 15,16,17