In vitro and cellular assays demonstrated that FSP1 prevents polyunsaturated fatty acid (PUFA)-enriched neutral lipid oxidation in LDs, thereby protecting cells from LD-mediated ferroptosis 22
As mentioned above, another central player in these redox systems is thioredoxin, which is reduced by NADPH to induce the transfer of electrons for use in DNA synthesis, signal transduction and redox regulation
However, continuous use of M
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