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This prevents the common mistake of attributing weight changes to medication effects when they actually result from dietary shifts during transitions

Wilding JP, Batterham RL, Calanna S, et al

If it has been around a month since your last injection, you may be advised to restart on the same dose or adjust the dose depending on how you tolerated treatment before

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Limited brain penetration of agonists: Studies using fluorescently labelled GLP-1 receptor agonists like semaglutide and liraglutide have shown very limited penetration into most brain regions beyond the circumventricular organs areas where the bloodbrain barrier is less effective and allows the brain to sample blood contents