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CSA did not elicit any probe response (Figure S1C), nor did other downstream products of oxidative Cys catabolism, including cysteate, sulfite or sulfate (Figure S1D-F)

(3) observational studies (cohort, case-control, cross-sectional) or experimental/preclinical evidence relevant to NSW-BC pathways

These findings are in line with studies indicating that milk for boys tends to have higher levels of free glutamine and glutamate than milk for girls in the first 3 to 4 months of lactation (35, 76), as boys are known to gain more weight and length than girls in this time period (77)

Additionally, Cbl deficiency has been associated with decreased immune function, such as reduced CD8 T cells and natural killer cells [29]