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The therapy effectiveness is rooted in its capacity to promote neovascularization and immunoregulation, both pivotal for repairing hypoxic-ischaemic necrosis in the femoral head [1, 47]

One of the interesting factors in ferroptosis regulation in SCD is through heme oxygenase 1 (Hmox1), which cleaves heme to form biliverdin and thus plays a protective role in vascular function 42,43,44,45

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While everyone's heard of GLP-1 agonists like semaglutide and tirzepatide, the amylin pathway remains relatively obscure despite producing comparable weight loss through an entirely different mechanism