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Enhanced Muscle Mass and Strength Growth hormone is crucial for protein synthesis

IGF-1 combats the loss of muscle mass in old age, both by promoting new tissue growth and retarding apoptosis (cell suicide that protects against infection and cancer, but that can kill healthy cells as we get older)

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[DOI] [PubMed] [Google Scholar] 57.Lacombe V., Patsouris A., Delattre E., Lacout C., Urbanski G

These body composition changes occurred without any measured change in food intake meaning the weight loss was driven by metabolic changes rather than appetite suppression