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According to the medicines' Summary of Product Characteristics (SmPCs), no dose adjustment is generally required for patients with mild to moderate hepatic impairment

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The inverse variance weighted (IVW) model was recruited as the primary two-sample MR analysis approach, followed by sensitivity analyses such as the heterogeneity test, horizontal pleiotropy test, leave-one-out analysis, and linkage disequilibrium score (LDSC) regression

Childhood obesity requires early, aggressive treatment, new guidelines say