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Three systematic reviews analyzing the risk of retained gastric contents causing premature termination of endoscopy have been published

The metabolic improvements from GLP-1 medications (weight loss, improved insulin sensitivity, reduced inflammation) combined with the cardiovascular benefits of estrogen replacement create a favorable risk profile

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Many patients report that maintaining this protocol feels natural on tirzepatide because hunger signals are already blunted, eliminating the willpower struggle that makes shorter eating windows difficult