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In the brain, GLP-1Rs are found in several hindbrain and forebrain sites, including areas that are implicated in the control of food intake and regulation of energy balance, such as the area postrema (AP), the nucleus tractus solitarius (NTS), hypothalamus, amygdala, and in the mesolimbic reward system

Knop: Despite the relatively small number of patients included in our study, it nevertheless represents one of the largest randomized, controlled trials investigating the effect of medical therapies for bile acid diarrhea

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P 5% weight loss in both HbA 1c and all BMI subgroups with no significant interactions

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