glp-1 and kidneys GLP-1s are back in the news — but this is a conversation we've explored on our channel before. From weight loss to heart, kidney, liver, sleep metabolic health, the science is SGLT2 vs GLP-1 for CKD:

Yes, a loading phase of several weeks with consistent administration is a standard part of most research protocols

same drug, different label) If you have moderate obesity (BMI 30 to 35): Semaglutide (Ozempic for diabetes, Wegovy for obesity) or liraglutide (Victoza for diabetes, Saxenda for obesity) If you want the simplest regimen: Once-weekly semaglutide or tirzepatide Goal: Minimize injection frequency Once weekly: Semaglutide, tirzepatide, dulaglutide, efpeglenatide, retatrutide Every two weeks (pipeline): Ecnoglutide (pending approval) Oral (no injections): Semaglutide (Rybelsus) or orforglipron (Orfoglip) Goal: Minimize gastrointestinal side effects Lower nausea profile: Tirzepatide (dual agonist

uniquely, the program reimburses payers should patients not achieve and then maintain weight loss following deprescription, allowing payers to avoid losses

How do we do it

4- to 6-week-old adult-born hippocampal neurons influence novelty-evoked exploration and contextual fear conditioning