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Among FXII inhibitors, the phase III trial results of garadacimab indicate its utility in the prophylaxis of hereditary angioedema attacks

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doi: 10.3389/fncel.2021.636176 Received 01 December 2020 Accepted 10 February 2021 Published 08 March 2021 Volume 15 - 2021 Edited by Jose Angel Morales-Garcia, Complutense University of Madrid, Spain Reviewed by Talita Glaser, University of So Paulo, Brazil

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Interactions with other receptors also occur, including ligand-gated ion channels, as well as GPCRs leading to homo- and heterodimer formation

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