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As a selective melanocortin 1 receptor (MC1R) agonist, afamelanotide is applied in experimental settings to probe the cAMP-mediated melanogenesis cascade the intracellular signaling pathway through which MC1R governs pigmentation biology in melanocyte cell models

Invert the vial and slowly pull back the plunger until you have exactly 1ml of liquid, free of air bubbles

Both have little clinical evidence behind them, however