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Existing studies, including those comparing the treatment with placebo, have focused primarily on evaluating the general safety and tolerability of the treatment, reporting predominantly mild or moderate adverse effects

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Ozempic side effects Trulicity and Ozempic can cause similar side effects in particular, mild gastrointestinal upset in the first few days-to-weeks of starting the medication or when you increase the dose

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Thigh injection may be the optimal starting site for retatrutide initiation , with gradual introduction of abdominal injection as tolerance develops