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Appetite & Metabolic Secondary Effects As a melanocortin receptor agonist with some activity beyond MC4R, PT-141 is also examined in research for secondary effects on appetite regulation and metabolic signaling though these effects are less pronounced than with the non-selective MT-II

This means that more food tends to be consumed before satiety signals are sent

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Cells were imaged by time-lapse microscopy with images taken every 6 seconds