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The additional GIP receptor engagement is thought to amplify satiety signaling in the hypothalamus and augment insulin secretion in a glucose-dependent fashion, without proportionally increasing nausea at therapeutic doses

Despite the antioxidative properties of VA being widely described in literature (Haymon 1957

B12 is generally considered safe in all life stages even at high doses and there are no known interactions with any medications, but some drugs can increase the risk of B12 deficiency, including acid-lowering drugs and metformin

This can happen for a variety of reasons

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